Funded by the ERA-NET Plant Genomics (ERA-NET PG) consortium, vSEED is a three year project working toward a mathematical model of a germinating Arabidopsis seed. ERA-Net PG is a collaborative network composed of European ministries, funding organizations, and national research councils with research programs in the area of plant genomics (www.erapg.org). The network currently includes 23 partners in 17 European countries.
vSeed website
The Virtual Seed Web Resource contains web-based tools for analysis of gene expression occurring during seed maturation, dormancy and germination.
Published Work
- Pearce S.P., King J.R., Holdsworth M.J. (2011) Axisymmetric indentation of curved elastic membranes by a convex rigid indenter. International Journal of Non-Linear Mechanics 46(9), 1128–1138
vSeed
- Bassel GW, Glaab E, Marquez J, Holdsworth MJ, Bacardit J (2011) Functional Network Construction in Arabidopsis Using Rule-Based Machine Learning on Large-Scale Data Sets. The Plant Cell 23, 3101–3116
vSeed
- Dupeux F, Santiago J, Betz K, Twycross J, Park S-Y, Rodriguez L, Gonzalez-Guzman M, Jensen M, Krasnogor N, Holdsworth MJ, Blackledge M, Cutler S, Rodriguez P, Marquez J (2011) A Thermodynamic Switch Modulates Abscisic Acid Receptor Sensitivity. EMBO Journal 30, 4171 – 4184
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- Bassel G, Holdsworth M, Provart N (2011) Seed bioinformatics. Methods in Molecular Biology 773 (8), 403–419
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- Bassel G.W., Lan H., Gibbs D.J., Gerjets T., Krasnogor N., Bonner A.J., Holdsworth M.J., Provart N.J. (2011) Genome-wide network model capturing seed germination reveals coordinated regulation of plant cellular phase transitions. Proceedings of the National Academy of Sciences of the United States of America 108, 9709–14
vSeed
- Holman TJ, Jones PD, Russell L, Medhurst A, Úbeda-Tomás S, Talloji P, Footitt S, Bachmair A, Theodoulou FL, Holdsworth MJ (2009) The N-end rule pathway promotes seed germination and establishment through removal of ABA sensitivity in Arabidopsis. PNAS 106, 4549–4554
vSeed
- Dietrich D, Schmuths H, DeMarcos Lousa C, Baldwin JM, Baldwin SA, Baker A, Theodoulou FL, Holdsworth M (2009) Mutations in the Arabidopsis ABC Transporter COMATOSE allow differentiation between different functions in planta: insights from an allelic series. Molecular Biology of the Cell 20, 530–543
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Presented Work
- Using engineering techniques to investigate plant biology questions. At: Annual Plant Biology Symposium at the University of Massachusetts Amherst 2011 Nicola Everitt, Darren Wells, Andy French
Virtual RootvSeed