MALDI-MSI: a new tool for metabolite analysis in forensic science

Michael Burrell, Simona Francese, Duncan D. Cameron, Chloe Steels, Malcolm Bennett, Darren Wells, Tara Holman & Jonathan Leake

Imaging matrix Assisted Laser Desorption mass spectrometry provides a new powerful tool to analyse the distribution of metabolites within plant or animal tissues and to compare with an untargeted approach different tissues or samples from different organisms. metabolites may be mapped at a single cell resolution and the technique may be used to resolve the differences between two samples of tissue.