Predicting function of plant polysaccharides synthesis enzymes

P Dupree, K Evans, SP Preston, M Segura & S White

Polysaccharides are the main constituents of the cell wall of plants. They are highly diverse, which suggests that many enzymes participate in their synthesis, and estimations based on plant genomes and homology of sequences reveal that a large number of protein families are indeed involved.
Determining gene function experimentally is laborious and time consuming, so when searching for genes that perform a specific function it is useful to prioritise candidates according to some measure of “closeness” to genes whose function is known. A promising way to prioritise is according to their localisation in cell compartments, since cellular functions tend to be performed by proteins grouped within the same organelle.

Proceedings of the 2nd Mathematics in the Plant Sciences Study Group